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1

Oral drug delivery with polymeric nanoparticles: The gastrointestinal mucus barriers

Laura M. Ensign, Richard Cone, Justin Hanes

Journal:

Advanced Drug Delivery Reviews

Year:

2012

Language:

english

File:

PDF, 1.80 MB

english, 2012

2

Enema ion compositions for enhancing colorectal drug delivery

Maisel, Katharina, Chattopadhyay, Sumon, Moench, Thomas, Hendrix, Craig, Cone, Richard, Ensign, Laura M., Hanes, Justin

Journal:

Journal of Controlled Release

Year:

2015

Language:

english

File:

PDF, 1010 KB

english, 2015

3

Impact of Surface Polyethylene Glycol (PEG) Density on Biodegradable Nanoparticle Transport in Mucus ex vivo and Distribution in vivo

Xu, Qingguo, Ensign, Laura M., Boylan, Nicholas J., Schön, Arne, Gong, Xiaoqun, Yang, Jeh-Chang, Lamb, Nicholas W., Cai, Shutian, Yu, Tao, Freire, Ernesto, Hanes, Justin

Journal:

Year:

2015

Language:

english

File:

PDF, 2.02 MB

english, 2015

4

Mucus-Penetrating Nanosuspensions for Enhanced Delivery of Poorly Soluble Drugs to Mucosal Surfaces

Yu, Tao, Chisholm, Jane, Choi, Woo Jin, Anonuevo, Abraham, Pulicare, Sarah, Zhong, Weixi, Chen, Minmin, Fridley, Colleen, Lai, Samuel K., Ensign, Laura M., Suk, Jung Soo, Hanes, Justin

Journal:

Advanced Healthcare Materials

Year:

2016

Language:

english

File:

PDF, 874 KB

english, 2016

5

Hypo-osmolar formulation of TFV enema promotes uptake and metabolism of TFV in tissues and leading to prevention of SHIV/SIV infection

Xiao, Peng, Gumber, Sanjeev, Marzinke, Mark A., Date, Abhijit A., Hoang, Thuy, Hanes, Justin, Ensign, Laura M., Wang, Lin, Rohan, Lisa, Fuchs, Edward J., Hendrix, Craig, Villinger, Francois

Journal:

Antimicrobial Agents and Chemotherapy

Year:

2017

Language:

english

File:

PDF, 5.45 MB

english, 2017

6

Nanoparticles coated with high molecular weight PEG penetrate mucus and provide uniform vaginal and colorectal distribution in vivo

Maisel, Katharina, Reddy, Mihika, Xu, Qingguo, Chattopadhyay, Sumon, Cone, Richard, Ensign, Laura M, Hanes, Justin

Journal:

Year:

2016

Language:

english

File:

PDF, 3.88 MB

english, 2016

7

Cancer Therapy: Vaginal Delivery of Paclitaxel via Nanoparticles with Non-Mucoadhesive Surfaces Suppresses Cervical Tumor Growth (Adv. Healthcare Mater. 7/2014)

Yang, Ming, Yu, Tao, Wang, Ying-Ying, Lai, Samuel K., Zeng, Qi, Miao, Bolong, Tang, Benjamin C., Simons, Brian W., Ensign, Laura M., Liu, Guanshu, Chan, Kannie W.Y., Juang, Chih-Yin, Mert, Olcay, Wood

Journal:

Advanced Healthcare Materials

Year:

2014

File:

PDF, 6.17 MB

2014

8

Particle tracking in drug and gene delivery research: State-of-the-art applications and methods

Schuster, Benjamin S., Ensign, Laura M., Allan, Daniel B., Suk, Jung Soo, Hanes, Justin

Journal:

Advanced Drug Delivery Reviews

Year:

2015

Language:

english

File:

PDF, 2.97 MB

english, 2015

9

Validation and implementation of liquid chromatographic-mass spectrometric (LC–MS) methods for the quantification of tenofovir prodrugs

Hummert, Pamela, Parsons, Teresa L., Ensign, Laura M., Hoang, Thuy, Marzinke, Mark A.

Journal:

Journal of Pharmaceutical and Biomedical Analysis

Year:

2018

Language:

english

File:

PDF, 942 KB

english, 2018

10

The penetration of fresh undiluted sputum expectorated by cystic fibrosis patients by non-adhesive polymer nanoparticles

Jung Soo Suk, Samuel K. Lai, Ying-Ying Wang, Laura M. Ensign, Pamela L. Zeitlin, Michael P. Boyle, Justin Hanes

Journal:

Year:

2009

Language:

english

File:

PDF, 561 KB

english, 2009

11

Development of a mucoinert progesterone nanosuspension for safer and more effective prevention of preterm birth

Hoang, Thuy, Zierden, Hannah, Date, Abhijit, Ortiz, Jairo, Gumber, Sanjeev, Anders, Nicole, He, Ping, Segars, James, Hanes, Justin, Mahendroo, Mala, Ensign, Laura M.

Journal:

Journal of Controlled Release

Year:

2019

Language:

english

File:

PDF, 4.48 MB

english, 2019

12

A poly(ethylene glycol)-based surfactant for formulation of drug-loaded mucus penetrating particles

Olcay Mert, Samuel K. Lai, Laura Ensign, Ming Yang, Ying-Ying Wang, Joseph Wood, Justin Hanes

Journal:

Journal of Controlled Release

Year:

2012

Language:

english

File:

PDF, 951 KB

english, 2012

13

Enhanced vaginal drug delivery through the use of hypotonic formulations that induce fluid uptake

Ensign, Laura M., Hoen, Timothy E., Maisel, Katharina, Cone, Richard A., Hanes, Justin S.

Journal:

Year:

2013

Language:

english

File:

PDF, 1.38 MB

english, 2013

14

Nanoparticles for oral delivery: Design, evaluation and state-of-the-art

Date, Abhijit A., Hanes, Justin, Ensign, Laura M.

Journal:

Journal of Controlled Release

Year:

2016

Language:

english

File:

PDF, 1.50 MB

english, 2016

15

Mucus Penetrating Nanoparticles: Biophysical Tool and Method of Drug and Gene Delivery

Laura M. Ensign, Craig Schneider, Jung Soo Suk, Richard Cone, Justin Hanes

Journal:

Advanced Materials

Year:

2012

Language:

english

File:

PDF, 997 KB

english, 2012

16

Ex Vivo Characterization of Particle Transport in Mucus Secretions Coating Freshly Excised Mucosal Tissues

Ensign, Laura M., Henning, Andreas, Schneider, Craig S., Maisel, Katharina, Wang, Ying-Ying, Porosoff, Marc D., Cone, Richard, Hanes, Justin

Journal:

Molecular Pharmaceutics

Year:

2013

Language:

english

File:

PDF, 1.12 MB

english, 2013

17

Nanoparticle-based drug delivery to the vagina: A review

Ensign, Laura M., Cone, Richard, Hanes, Justin

Journal:

Journal of Controlled Release

Year:

2014

Language:

english

File:

PDF, 1.84 MB

english, 2014

18

Controlled release of dexamethasone sodium phosphate with biodegradable nanoparticles for preventing experimental corneal neovascularization

Wang, Bing, Tang, Yating, Oh, Yumin, Lamb, Nicholas W., Xia, Shiyu, Ding, Zheng, Chen, Baiwei, Suárez, María J., Meng, Tuo, Kulkarni, Vineet, Eberhart, Charles G., Ensign, Laura M., Stark, Walter J.,

Journal:

Nanomedicine: Nanotechnology, Biology and Medicine

Year:

2019

File:

PDF, 1.02 MB

2019

19

Editorial

Hanes, Justin, Ensign, Laura, Kannan, Rangaramanujam, Soo Suk, Jung

Journal:

Journal of Controlled Release

Year:

2015

Language:

english

File:

PDF, 114 KB

english, 2015

20

Nanoparticles that do not adhere to mucus provide uniform and long-lasting drug delivery to airways following inhalation

Schneider, Craig S., Xu, Qingguo, Boylan, Nicholas J., Chisholm, Jane, Tang, Benjamin C., Schuster, Benjamin S., Henning, Andreas, Ensign, Laura M., Lee, Ethan, Adstamongkonkul, Pichet, Simons, Brian

Journal:

Science Advances

Year:

2017

Language:

english

File:

PDF, 2.40 MB

english, 2017

21

Pseudomonas aeruginosa Pyocyanin Production Reduced by Quorum-Sensing Inhibiting Nanocarriers

Lu, Hoang D., Pearson, Elizabeth, Ristroph, Kurt D., Duncan, Gregg A., Ensign, Laura M., Soo Suk, Jung, Hanes, Justin, Prud'homme, Robert K.

Journal:

International Journal of Pharmaceutics

Year:

2018

Language:

english

File:

PDF, 1.50 MB

english, 2018

22

Anti-PEG antibodies alter the mobility and biodistribution of densely PEGylated nanoparticles in mucus

Henry, Christine E., Wang, Ying-Ying, Yang, Qi, Hoang, Thuy, Chattopadhyay, Sumon, Hoen, Timothy, Ensign, Laura M., Nunn, Kenetta L., Schroeder, Holly, McCallen, Justin, Moench, Thomas, Cone, Richard,

Journal:

Acta Biomaterialia

Year:

2016

Language:

english

File:

PDF, 1.68 MB

english, 2016

23

North America special issue Part II

Hanes, Justin, Ensign, Laura M., Kannan, Rangaramanujam, Suk, Jung Soo

Journal:

Journal of Controlled Release

Year:

2016

Language:

english

File:

PDF, 109 KB

english, 2016

24

Vaginal Delivery of Paclitaxel via Nanoparticles with Non-Mucoadhesive Surfaces Suppresses Cervical Tumor Growth

Yang, Ming, Yu, Tao, Wang, Ying-Ying, Lai, Samuel K., Zeng, Qi, Miao, Bolong, Tang, Benjamin C., Simons, Brian W., Ensign, Laura M., Liu, Guanshu, Chan, Kannie W.Y., Juang, Chih-Yin, Mert, Olcay, Wood

Journal:

Advanced Healthcare Materials

Year:

2014

Language:

english

File:

PDF, 1.09 MB

english, 2014

25

Vaginal Microbiota Transplantation: The Next Frontier

DeLong, Kevin, Zulfiqar, Fareeha, Hoffmann, Diane E., Tarzian, Anita J., Ensign, Laura M.

Journal:

The Journal of Law, Medicine & Ethics

Year:

2019

Language:

english

File:

PDF, 170 KB

english, 2019

26

Liposome-based mucus-penetrating particles (MPP) for mucosal theranostics: Demonstration of diamagnetic chemical exchange saturation transfer (diaCEST) magnetic resonance imaging (MRI)

Yu, Tao, Chan, Kannie W.Y., Anonuevo, Abraham, Song, Xiaolei, Schuster, Benjamin S., Chattopadhyay, Sumon, Xu, Qingguo, Oskolkov, Nikita, Patel, Himatkumar, Ensign, Laura M., van Zjil, Peter C.M., McM

Journal:

Nanomedicine: Nanotechnology, Biology and Medicine

Year:

2015

Language:

english

File:

PDF, 1.42 MB

english, 2015

27

Effect of surface chemistry on nanoparticle interaction with gastrointestinal mucus and distribution in the gastrointestinal tract following oral and rectal administration in the mouse

Maisel, Katharina, Ensign, Laura, Reddy, Mihika, Cone, Richard, Hanes, Justin

Journal:

Journal of Controlled Release

Year:

2015

Language:

english

File:

PDF, 3.27 MB

english, 2015

28

The Microstructure and Bulk Rheology of Human Cervicovaginal Mucus Are Remarkably Resistant to Changes in pH

Wang, Ying-Ying, Lai, Samuel K., Ensign, Laura M., Zhong, Weixi, Cone, Richard, Hanes, Justin

Journal:

Biomacromolecules

Year:

2013

Language:

english

File:

PDF, 1.32 MB

english, 2013

29

Modulating Vibrio cholerae Quorum-Sensing-Controlled Communication Using Autoinducer-Loaded Nanoparticles

Lu, Hoang D., Spiegel, Alina C., Hurley, Amanda, Perez, Lark J., Maisel, Katharina, Ensign, Laura M., Hanes, Justin, Bassler, Bonnie L., Semmelhack, Martin F., Prud’homme, Robert K.

Journal:

Year:

2015

Language:

english

File:

PDF, 1.21 MB

english, 2015

30

Nano-structured glaucoma drainage implant safely and significantly reduces intraocular pressure in rabbits via post-operative outflow modulation

Parikh, Kunal S., Josyula, Aditya, Omiadze, Revaz, Ahn, Ju Young, Ha, Youlim, Ensign, Laura M., Hanes, Justin, Pitha, Ian

Journal:

Scientific Reports

Year:

2020

File:

PDF, 2.16 MB

2020

31

Sunitinib malate-loaded biodegradable microspheres for the prevention of corneal neovascularization in rats

Yang, Jin, Luo, Lixia, Oh, Yumin, Meng, Tuo, Chai, Guihong, Xia, Shiyu, Emmert, David, Wang, Bing, Eberhart, Charles G., Lee, Seulki, Stark, Walter J., Ensign, Laura M., Hanes, Justin, Xu, Qingguo

Journal:

Journal of Controlled Release

Year:

2020

File:

PDF, 4.93 MB

2020

32

Local enema treatment to inhibit FOLH1/GCPII as a novel therapy for inflammatory bowel disease

Date, Abhijit A., Rais, Rana, Babu, Taarika, Ortiz, Jairo, Kanvinde, Pranjali, Thomas, Ajit G., Zimmermann, Sarah C., Gadiano, Alexandra J., Halpert, Gilad, Slusher, Barbara S., Ensign, Laura M.

Journal:

Journal of Controlled Release

Year:

2017

Language:

english

File:

PDF, 674 KB

english, 2017

33

Sustained delivery of acriflavine from the suprachoroidal space provides long term suppression of choroidal neovascularization

Hackett, Sean F., Fu, Jie, Kim, Yoo Chun, Tsujinaka, Hiroki, Shen, Jikui, Lima e Silva, Raquel, Khan, Mahmood, Hafiz, Zibran, Wang, Tao, Shin, Matthew, Anders, Nicole M., He, Ping, Ensign, Laura M., H

Journal:

Year:

2020

File:

PDF, 2.68 MB

2020

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